This study evaluates the PSG and cerebral metabolism and functions in narcolepsy with/without RBD
Polysomnographic (PSG) work-up one night to record nocturnal sleep condition in narcolepsy with /without RBD and control subjects including sleep macrostructure, occurrence of sleep onset rapid eye movement period(SOREMP), sleep stages distribution, and sleep arousle and leg movement and apnea hyponea index would be calculated. Functional magnetic resonance imaging (fMRI) has been used in human to nonivasiverlyn investigate the neural mechanisms. This technique also apply to measures the variations in brain perfusion, structure and morphology in narcolepsy patients by assessing the blood oxygen level-dependent (BOLD) signal diffusion tensor imaging (DTI and voxel-based morphometry(VBM) This study compare the feature of PSG and fMRI between narcolepsy with RBD, narcolepsy without RBD, control subject to evaluates the PSG and cerebral metabolism and functions in narcolepsy with/without RBD.
Study Type
OBSERVATIONAL
Enrollment
100
Tangdu Hospital
Xi'an, Shaanxi, China
RECRUITINGvideo-polysomnographic(PSG)
video-PSG monitor sleep from 9:00pm to 6:00am
Time frame: up to 100 weeks
multiple sleep latency test (MSLT)
MSLT in the next day of PSG record daytime sleepiness
Time frame: up to 100 weeks
functional magnetic resonance imaging (fMRI)
All narcolepsy with or withoutRBD accepts fMRI
Time frame: up to 100 weeks
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.