Novel Equation for Estimating Resting Energy Expenditure

Peking University First Hospital300 enrolled

Overview

The energy and nutrition states are closely associated with CKD patients complications and outcomes.To reach the energy balance target, we need the accurate resting energy expenditure level of patients. Traditional equations are not applicable to CKD patients,so we aim to develop and validate a equation for estimating resting energy expenditure in CKD patients.

Study Type

OBSERVATIONAL

Enrollment

300

Conditions

Resting Energy Expenditure Chronic Kidney Disease

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * CKD 3-5 stages * Age:18-80 years old Exclusion Criteria: * Dialysis and kidney transplantation; * Acute complications to hospitalization * 1 month prior to the study; * Acute or chronic infections, cancer and other wasting diseases in the past year; * Thyroid dysfunction; * Acute onset of podagra; Musculoskeletal diseases; * Respiratory diseases (asthma, pleural effusion, pneumothorax, COPD); * History of hormonal drugs use; * During pregnancy or lactation

Locations (1)

Renal Division and Institute of Nephrology, Peking University First Hospital

Beijing, Beijing Municipality, China

Outcomes

Primary Outcomes

Novel equation development

Developed equation for estimating REE in CKD 3-5 stages patients

Time frame: September 1, 2017 to June 1, 2018

Novel equation validation

Validate the noval equation with REE obtained by indirect calorimetry (IC).

Time frame: June 1, 2018 to March 1, 2019

Data from ClinicalTrials.gov

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