A fever and a non-blanching rash is a relatively common reason for a child to attend an emergency department. A fever and a non-blanching rash can be an early sign of a life-threatening infection known as meningococcal disease. The aim of the PIC study is to determine how best to diagnose early meningococcal disease in children. In particular the investigators are interested in researching how quick bedside tests can be used to do this.
A fever an a non-blanching rash is a relatively common presentation the the emergency department. A minority of children with a fever and a non-blanching rash with have a life-threatening infection. Currently it is very difficult to determine those children that require urgent treatment from those that have a simple viral illness. The aim of the PIC study is to research how to better diagnose those serious infections earlier. Data from the study will be used to test the effectiveness of current practice and to identify areas where current practice could be improved.
Study Type
OBSERVATIONAL
Enrollment
1,329
Royal Belfast Hospital for Sick Children
Belfast, Northern Ireland, United Kingdom
Confirmation of meningococcal infection
Blood and Cerebrospinal fluid (CSF) culture or quantitative Polymerase Chain Reaction (PCR) will be used to confirm meningococcal infection
Time frame: 72 hours from testing
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