A randomized, open-label, active-controlled, multiple dose phase 1 clinical trial to evaluate safety, tolerability, and pharmacodynamics of tegoprazan after oral administration in healthy male volunteers
* To compare the pharmacodynamics of multiple oral dose of tegoprazan versus the pharmacodynamics of multiple oral dose of comparator drug in healthy male volunteers. * To evaluate the safety and tolerability of multiple oral dose of tegoprazan in healthy male volunteers.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
16
Tegoprazan QD for 7 days
Revaprazan QD for 7 days
Seoul National University Hospital
Seoul, South Korea
Gastric pH
Gastric pH
Time frame: up to 7 days
Serum gastrin concentration
Serum gastrin concentration
Time frame: up to 9 days
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