SouthErn China REgisTry for Stroke on Traditional Chinese Medicine

Yefeng Cai10,000 enrolled

Overview

Stroke is the first most common cause of death in China and one of the major causes of functional disability in the adult population.The burden of stoke is significantly increased in China in recent years. In order to investigate the prognosis of stroke, with diagnostic and treatment information of traditional Chinese medicine (TCM), and assess the effectiveness and safety of TCM for stroke in southern China, the investigators will conduct this multicenter prospective registry study in southern China. This study will recruit 10,000 consecutive eligible patients with acute stroke from more than 50 hospitals. 24 months follow-up will be carried out on-site in hospitals and by telephone to track endpoint (including all-cause mortality, composite cerebrovascular and cardiovascular events at one and two year follow up, and neurological and functional assessments).

Study Type

OBSERVATIONAL

Enrollment

10,000

Conditions

Stroke Cerebral Infarction Transient Ischemic Attack Cerebral Hemorrhage Subarachnoid Hemorrhage

Interventions

observational only-no interventionOTHER

Observational only and no predesigned interventions in this study.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. ≥18 years. 2. Patients within 14 days of onset of acute stroke (including acute cerebral infarction, transient ischemic attack, acute cerebral hemorrhage, acute subarachnoid hemorrhage). 3. The patient and/or guardian agree to participate in this study. Exclusion Criteria: 1. Patients with silent cerebrovascular disease. 2. Patients with non-cerebrovascular disease events.

Locations (1)

Wuyi Traditional Chinese Medicine Hospital of Jiangmen

Jiangmen, Guangdong, China

RECRUITING

Outcomes

Primary Outcomes

All-cause mortality

Time frame: 12 months follow-up

Composite cerebrovascular and cardiovascular events

Including stroke recurrence events,acute myocardial infarction and cardiac death

Time frame: 12 months follow-up

Secondary Outcomes

All-cause mortality

Time frame: 24 months follow-up

Composite cerebrovascular and cardiovascular events

Including stroke recurrence events,acute myocardial infarction and cardiac death

Time frame: 24 months follow-up

Modified Rankin Scale(mRS)

Range:Grade 0 to Grade 6, higher grade represent a worse outcome

Time frame: 3 months follow-up

Barthel Index(BI)

Range:0 to 100 points, higher points represent a better outcome

Time frame: 3 months follow-up

Mini-Mental State Examination(MMSE)

Range:0 to 30 points, higher points represent a better outcome

Time frame: 3 months follow-up

Modified Rankin Scale(mRS)

Range:Grade 0 to Grade 6, higher grade represent a worse outcome

Time frame: 12 months follow-up

Barthel Index(BI)

Range:0 to 100 points, higher points represent a better outcome

Time frame: 12 months follow-up

Mini-Mental State Examination(MMSE)

Range:0 to 30 points, higher points represent a better outcome

Time frame: 12 months follow-up

Modified Rankin Scale(mRS)

Range:Grade 0 to Grade 6, higher grade represent a worse outcome

Time frame: 24 months follow-up

Barthel Index(BI)

Range:0 to 100 points, higher points represent a better outcome

Time frame: 24 months follow-up

Mini-Mental State Examination(MMSE)

Range:0 to 30 points, higher points represent a better outcome

Time frame: 24 months follow-up

Central Contacts

Yefeng Cai, M.D.,PhD

CONTACT

+86-13631333842 caiyefeng@126.com

Xinfeng Guo, PhD

CONTACT

+86-13678906862 guoxinfeng@gzucm.edu.cn

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.