Study of Speech Disorders , Voice and Swallowing in Primary Dystonia Oromandibular

University Hospital, Lille28 enrolled

Overview

To better define the clinical characteristics of oromandibular dystonia, we aimed to study voice, speech and swallowing disorders in idiopathic oromandibular We planned to include consecutive patients followed in Lille Movement disorders department for idiopathic oromandibular dystonia and matched, healthy control subjects. Voice and speech disorders had to be assessed with the phonetic analysis, perceptive analysis and motor examination modules of the "Batterie d'Evaluation Clinique de la Dysarthrie" (Clinical Evaluation of Dysarthria), the Grade, Rough, Breathy, Asthenic, Strained scale, and a computer recording. Activities of daily living had to be assessed with the Oromandibular Dystonia Questionnaire, the Voice Handicap Index and the Deglutition Handicap Index.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Dystonia, Primary Dysarthria Dysphonia Dysphagia

Eligibility

Sex: ALLMin age: 8 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Both groups: Man or woman Age \> 18 years French social security French speaking: fluent * Oromandibular dystonia group: Idiopathic oromandibular dystonia (focal or associated to other dystonic symptoms) * Healthy controls group: Same age +/- 2 years than a patient from the oromandibular dystonia group Normal clinical examination Exclusion Criteria: * Both groups: Any pathology making the orthophonic evaluation difficult Property protection regime Deprivation of liberty -Oromandibular dystonia group: Abnormal neurological examination, except dystonic features * Healthy controls group: History of brain lesion Abnormal neurological examination Swallowing difficulties

Outcomes

Primary Outcomes

French scale "Batterie d'Evaluation Clinique de la Dysarthrie" (Clinical Evaluation of Dysarthria) phonetic analysis.

To describe the clinical characteristics of dysarthria in idiopathic oromandibular dystonia. Composite score (min=best=0; max=worst=151) including three subscales: phonetic production (min=worst=0; max=best=33); simple words (min=worst=0; max=best=88); complex words (min=wost=0; max=best=30).

Time frame: 10 minutes at baseline

Secondary Outcomes

French software "Logiciel d'Evaluation Vocale Assistée" (Computer-Assisted Voice Assessment): maximum phonation time

To describe the clinical characteristics of voice impairment in idiopathic oromandibular dystonia. Maximum phonation time was measured in seconds.