Clinical Trial to eLiminate HCV-infection in Treatment-naïve, Renally Impaired EgyptiAn Patients on Renal Dialysis, With Chronic Hepatitis C Genotype 4

Inclusion Criteria: 1. Signed and dated informed consent obtained before undergoing any trial-related procedures 2. Male and female patients; age between 21 and 70 years inclusive 3. Chronic hepatitis C infection with genotype 4 confirmed by genotypic testing at screening or within 6 months of screening period 4. Treatment naïve - absence of prior failed treatment for HCV with Interferon plus ribavirin therapy or directly acting antivirals (treatment experienced) 5. Detectable HCV viral load (quantitative) 6. Liver cirrhosis subjects may be included but will be limited to those with compensated liver disease 7. Chronic kidney disease with end-stage liver disease (defined as glomerular filtration rate \[eGFR\] \<=15 mL/min/1.73m2) on hemodialysis for at least 3 months, including individuals awaiting kidney transplant and those with failed kidney transplants but no longer on immunosuppressant therapy) 8. Screening laboratory values within the defined protocol thresholds 9. Women of child-bearing potential, must agree to abstinence or use of effective contraceptive methods (e.g. oral or injectable contraceptives, intra-uterine device (IUD), transdermal contraceptive patch) at least 2 weeks prior Day 1 through 14 days after the last dose of the study drug. 10. Ability to communicate, participate, and comply with the requirements of the entire study Exclusion Criteria: 1. Patients didn't sign informed consent or under age of legal consent 2. Pregnant or breastfeeding woman 3. Has HCV genotypes other than G4 4. On peritoneal dialysis for management of kidney disease 5. Co-Infection with HIV and/or HBV (with positive HBsAg) 6. Evidence of hepatocellular carcinoma (HCC) 7. Evidence of hepatic decompensation as evidenced by presence or history of ascites, esophaegal or gastric bleeding, hepatic encelopathy or other signs of or symptoms of advanced liver disease, or cirrhotic subjects with Child-Pugh B or C, or who have a Purgh-Turcotte (CPT) score \>6 8. Active or suspected non-hepatic malignancy or history of any malignancy except for cured basal cell or squamous cell skin cancer or in situ cervical cancer 9. Organ transplant (including hematopoietic stem cell transplant) other than kidney, cornea, and hair 10. Conditions requiring, or likely to require, chronic systemic administration of corticosteroids during the course of the trial 11. Uncontrolled or poorly controlled hypertension 12. Pregnant, breast-feeding, expecting to conceive or donate eggs, or donate sperm from Day 1 through 14 days after the last study dose. 13. Significant cardiovascular disorder (e.g. myocardial infarction or unstable angina) or interventional cardiovascular procedure within 3 months prior to signing informed consent 14. Recent (within 3 months prior to signing informed consent) episode or recurrence of stroke, transient ischemic attack (TIA) or neurological disorder, including but not limited to seizures 15. ALT or AST \> 10-fold the upper limit of normal 16. Evidence of liver disease due to causes other than chronic HCV infection 17. Evidence of poorly controlled diabetes (defined as HbA1c \> 8%) 18. History of alcohol or drug abuse within the last 12 months 19. Serum albumin level \< 3.0 g/dL 20. INR \> 1.3 N 21. Total Bilirubin levels \> 2.0 mg/dL unless explained by Gilbert's disease 22. Platelets Count \<75,000/µL 23. White blood cell count \< 1500 µL (mm3) 24. Clinically significant TSH and T4 level poorly controlled thyroid function 25. Patients with any abnormality on physical examination, vital signs (sitting systolic blood pressure greater than 150 mmHg, sitting diastolic blood pressure greater than 90 mmHg and pulse greater than 90 bpm) and ECG, unless these abnormalities are judged to be not clinically significant by the Investigator 26. Body Mass Index \< 18.5 or \> 35 kg/m2 27. Use of other investigational drugs/treatments within the previous 3 months 28. Known hypersensitivity to any of the test materials or related compounds. 29. Active autoimmune disease. 30. History of moderate, severe or uncontrolled psychiatric disease, especially severe depression and prior suicidal attempt. 31. Unable to comply with research study visits. 32. Poor venous access not allowing screening laboratory collection. 33. Any other condition that, in the opinion of the Investigator, may be a contraindication to study participation or jeopardize the study conduct according to the protocol.