Nutrition Status, BMD, and SSRIs

University of New Mexico13,027 enrolled

Overview

The association between selective serotonin reuptake inhibitor (SSRI) use and bone mass density (BMD) has been debated. Some have suggested features of depression, which SSRIs are prescribed to treat, may be a cause of decreased BMD, such as poor overall food intake at the time of SSRI use. Our study seeks to determine whether SSRI use in adults is associated with lower than average BMD, and if there is an association between low micronutrient intake, SSRI use, and a low BMD.

Study Type

OBSERVATIONAL

Enrollment

13,027

Conditions

BMD

Interventions

Dual-Energy X-ray Absorptiometry (DXA)DIAGNOSTIC_TEST

BMD t-score derived from DXA scan

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Included adult NHANES participants are those who participated in the Dual-Energy X-ray Absorptiometry (DXA) femur-neck BMD test and responded in full to the demographic, pharmaceutical, and dietary surveys. Exclusion Criteria: * Pregnancy, incomplete survey responses, incomplete DXA results

Outcomes

Primary Outcomes

BMD t-score

Time frame: NHANES DXA measurement taken 2005-2014

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.