CD30 Targeted CAR-T in Treating CD30-Expressing Lymphomas

Inclusion Criteria: Hodgkin's lymphoma, anaplastic large cell lymphoma and other CD30 positive malignancies, relapsed or refractory: * Karnofsky or Lansky score \>50; * Expected survival\>12 weeks; * Hgb \> 8.0; * FEV1, FVC and DLCO ≥50% of expected corrected for hemoglobin; * LVEF≥50%; * Creatinine\<2.5mg/dl; * Bilirubin\<2.5mg/dl; * ALT (alanine aminotransferase)/AST (aspartate aminotransferase)\<3 fold normal; * Patients must sign an informed consent. Exclusion Criteria: * Pregnant or lactating; * Uncontrolled active infection including hepatitis B or C; * HIV positive; * Active clinically significant CNS dysfunction; * Current use of systemic steroids; * Heterogenous lymphocyte treatments within recent 6 months;