Trial design: a randomized controlled trial. Eligibility criteria for participants: patients with primary early stage oral squamous cell carcinoma. Exclusion criteria: cancer of the floor of the mouth. Interventions: submandibular gland is preserved during neck dissection for patients of the experimental group; submandibular gland is removed during neck dissection for patients of the control group. Primary Parameters: survival rate, mortality rate
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
200
Modified neck dissection with preservation of submandibular gland. The submandibular gland is preserved during neck dissection.
traditional neck dissection without preservation of submandibular gland
Peking University School of Stomatology
Beijing, Beijing Municipality, China
RECRUITING5-year survival rate
disease free survival rate
Time frame: 5-year after operation
3-year survival rate
disease free survival rate
Time frame: 3-year after operation
5-year regional recurrence rate
rate of participants with tumor recurrence in the neck
Time frame: 5-year after operation
3-year regional recurrence rate
rate of participants with tumor recurrence in the neck
Time frame: 3-year after operation
1-year regional recurrence rate
rate of participants with tumor recurrence in the neck
Time frame: 1-year after operation
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