Since exogenous surfactant replacement therapy was first used to prevent neonatal respiratory distress syndrome (NRDS)，it has become the main method of treatment of NRDS. However, in some infants, death is inevitable despite intensive care and surfactant replacement therapy, especially in near-term and term infants. The first goal of our study is to compare the therapeutic effect of pulmonary surfactant of infants at different gestational ages and to investigate whether exogenous surfactant replacement therapy is effective for all newborns with RDS. The second goal of our study is to further analyze the risk factors and causes of RDS in early preterm infants and near term/term infants.
Study Type
OBSERVATIONAL
Enrollment
1,500
All NRDS were given an early endotracheal infusion of Curosuf, with an initial dose of 200mg/kg, and if the condition needed to be repeated. Compare the therapeutic effect of pulmonary surfactant of infants at different gestational ages and to investigate whether exogenous surfactant replacement therapy is effective for all newborns with RDS.
Compare the perinatal risk factors that were closely related to NRDS between early preterm infants with RDS and near term/term infants with RDS.
Department of pediatrics, Daping Hospital, The Third Military Medical University
Chongqing, Chongqing Municipality, China
RECRUITINGtherapeutic effect of pulmonary surfactant of infants at different gestational ages
Time frame: January 1，2011 to December 30，2016
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.