This study is a non invasive study to see if 100% oxygen therapy will help to resolve an intestinal obstruction.
TOGA involves the provision of a 6- hour treatment with 100% oxygen via non breather mask to hospitalized patients with ileus, small bowel obstruction and/or colonic pseudo-obstruction will be a useful supplemental therapy, decreasing the diameter of the intestinal lumen and enhancing resolution of ileus/pseudo-obstruction
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
17
To provide hospitalized ileus or pseudo-obstruction patient with 100% oxygen via non-rebreather face mask, for 6 hours
University of Florida
Gainesville, Florida, United States
Changes in Diameter of Colon
X-ray of kidney, ureter and bladder (KUB) to determine maximal cecal diameter, maximal mid-transverse colon diameter, maximal mid-sigmoid colon diameter.
Time frame: 6 - 24 hours
Changes in Diameter of the Small Bowel
X-ray of kidney, ureter and bladder (KUB) to determine maximal cecal diameter, maximal mid-transverse colon diameter, maximal mid-sigmoid colon diameter.
Time frame: 6 - 24 hours
Demonstrates No Resolution of Ileus
A second treatment with TOGA will be offered.
Time frame: 24 - 30 hours after initial TOGA
Worsening of Ileus
Worsening of ileus after initial treatment but not requiring surgical or endoscopic intervention, will be offered a second treatment of TOGA.
Time frame: 24 - 30 hours after initial TOGA
Need for endoscopic or surgical intervention
Worsening of ileus after initial treatment, requiring surgical or endoscopic intervention
Time frame: 24 - 30 hours after initial TOGA
Length of Hospital Stay
Length of stay, measured at the end of hospitalization
Time frame: up to 100 weeks
Patient Complaints
Recording of patient perception/tolerance \[daily\] of TOGA.
Time frame: Up to 48 hours
Patient Pain Measurement
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Patient pain measurement determined subjectively through a visual analogue scale (VAS) scale of 0 (no pain) to 10 (worst pain imaginable) taken before and after TOGA treatment.
Time frame: Up to 48 hours
Medication Measurement
Documenting medication requirements for patients exposed to TOGA.(past 24 hours on a scale of 0 (no pain) to 10 (worst pain imaginable)
Time frame: 24 hours before through 24 hours after TOGA