The investigators developed an ultra-speed picosecond laser (20ps) with a 20gHz repetition rate that provide very promising results in vitro and in ex vivo skin to remove skin tattoos. The aim of this study is to evaluate the efficacy and tolerance of a new ultra-speed picosecond laser and to compare it to a nanosecond laser for treating black tattoos. In a first phase of the study 10 patients with black tattoos will be treated with increasing fluencies of the picosecond laser to the optimal parameters in terms of efficacy and tolerance. In a second phase, 10 additional subjects with black tattoos will be treated after central randomization on half of the tattoo with the picosecond laser (with the parameters determined in the first phase) and the other half treated with a nanosecond laser.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
18
Laser utilisation for tattoo depigmentation 1 session every month for a total of 3 sessions
Laser utilisation for tattoo depigmentation 1 session every month for a total of 3 sessions
CHU de Nice - Dermatologie - Hôpital Archet
Nice, France
Percentage of decrease of tattoos 2 months after the third session as compared to baseline on standardized pictures
Time frame: 2 month after the end of laser utilisation
Evaluation of Pain with EVA test
Time frame: 2 months after one session of laser utilisation
Evaluation of tolerance
correlation between EVA test and dermatological clinical signs
Time frame: 2 months after one session of laser utilisation
satisfaction evaluation of depigmanetation tattoo
satisfaction tests
Time frame: 2 months after one session of laser utilisation
Skin biopsies
Time frame: immediately after treatment
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