Biomarkers in Patients Undergoing Atrial Fibrillation Ablation

Universitätsklinikum Hamburg-Eppendorf300 enrolled

Overview

The investigators aim to find biomarkers to determine the success of pulmonary vein isolation for the treatment of atrial fibrillation.

The investigators perform an observational study in patients undergoing pulmonary vein ablation to treat atrial fibrillation. Additionally, electrophysiological procedures not related to pulmonary vein isolation are also followed. The aim of the study is finding biomarkers that are able to predict short-term outcome of the procedure.The primary endpoint is defined as reoccurrences of atrial fibrillation within the first three months after pulmonary vein isolation.

Study Type

OBSERVATIONAL

Enrollment

300

Conditions

Atrial Fibrillation

Interventions

Catheter AblationPROCEDURE

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * patients with atrial fibrillation scheduled for pulmonary vein isolation with either radiofrequency of cryoballoon * patients scheduled for an electrophysiological study without ablation * patients with a catheter ablation at the cavotricuspid isthmus for the treatment of right atrial flutter Exclusion Criteria: * patients with concurrent pulmonary vein isolation and ablation of the cavotricuspid isthmus * Acute myocardial infarction, coronary artery bypass graft surgery or open heart surgery within less than 3 months prior to inclusion

Locations (1)

Department of Cardiology - Electrophysiology, University Heart Centre, University Hospital Hamburg-Eppendorf

Hamburg, Germany

Outcomes

Primary Outcomes

Number of patients with short term reoccurrences of atrial fibrillation after ablation.

Holter ECGs and ECGs after atrial fibrillation ablation

Time frame: 3 months

Secondary Outcomes

Change in heart rate after pulmonary vein isolation

Heart rates are recorded at admission and release from the hospital.

Time frame: 3 days.

Data from ClinicalTrials.gov

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