This case-control study aims to compare the pelvic microbiomes of benign ovarian diseases and ovarian malignancies by 16s RNA techniques and culture. Discharges/flushing fluid from vagina, faces and fimbria end of fallopian tube are collected from age and menopausal status matched patient before and during procedures of laparoscopies. The discharges/flushing fluid would be sent for 16s RNA analysis and microculture respectively, and the results would get self-contrasted comparison and case-control comparison.
Study Type
OBSERVATIONAL
Enrollment
40
16s RNA analysis and microculture of discharges/flushing fluid from vagina, faces and fimbria end of fallopian tube
Peking Union Medical College Hospital
Beijing, Beijing Municipality, China
RECRUITINGDifference of species distribution of microorganism according to 16s RNA analysis
The difference of species of microorganism distribution according to 16s RNA sequencing analysis between control group and study group, and between different sampling sites in each arm
Time frame: 2 years
Difference of species distribution of microorganism according to microculture outcomes
Difference of species distribution of microorganism according to microculture outcomes between control group and study group, and between different sampling sites in each arm
Time frame: 2 years
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