Misoprostol Versus Active Management of Labour in CS

Aljazeera Hospital300 enrolled

Overview

Several treatment strategies are emplemented to prevent post delivery hemorage and decreasing maternal morbidity and mortality .

Many approved drugs are used in prophylaxis against postpartum hemorage from these medications are the (syntocinon combined with methergine ) that are known as active management of labour drugs . Moreover there is misotac , that also guards against postpartum hemorage . All these medications act in a different way to cause uterine contraction post delivery to prevent uterine atony . -Here we are comparing the additive value of misotac intrauterine to syntocinon and methergine in comparison to the usually used syntocinon plus methergine .

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

DOUBLE

Enrollment

300

Conditions

Cesarean Section

Interventions

Misoprostol + syntocinon and using extra uterotonic drugs when needed ; methergineDRUG

medical prophylaxis against postpartum atony and postpartum hemorage by giving misoprostol plus syntocinon and using extra uterotonic drugs when needed ; methergine, carboprost

Syntocinon and using extra uterotonic drugs when needed ; methergine carboprostDRUG

medical prophylaxis against postpartum atony and postpartum hemorage by giving syntocinon and using extra uterotonic drugs when needed ; methergine, carboprost

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 42 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * • All patients included in this research were aged 18-42 years, pregnant 37 weeks till 42 weeks * no medical disorders with pregnancy e.g DM, HTN. All patients were subjected to full history taking, examination. Exclusion Criteria: * Exclusion Criteria: * The following patients were excluded , GA before 37 weeks or after 42 weeks , medical disorders with pregnancy eg. DM with pregnancy, HTN with pregnancy

Locations (1)

Algazeerah

Giza, Egypt

Outcomes

Primary Outcomes

The number of participants who passed cesarean section without postpartum hemorage

Time frame: within 2 days post CS

Data from ClinicalTrials.gov

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