The purpose of this study is to investigate the effects of dexmedetomidine infusion on the stress response to intubation, postoperative analgesia, and renal functions (urinary output \[UOP\], creatinine and glomerular filtration rate \[GFR\]) in preeclamptic patient.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
30
Caesarian section will be performed under standard general anesthesia plus pre and intra operative saline infusion (placebo) in the same rate as dexmedetomedine starting 15 minutes before induction of general anesthesia and continue till peritoneum closure.
Caesarian section will be performed under standard general anesthesia plus pre and intra operative Dexmedetomidine infusion in a dose of 0.5mic/kg/hour starting 15 minutes before induction of general anesthesia and continue till peritoneum closure.
South Egypt Cancer Institute
Asyut, Egypt
postoperative analgesia
through VAS score readings
Time frame: 24 hours postoperatively
stress response
mean arterial blood pressure
Time frame: 24 hours postoperatively
renal function
glomerular filtration rate
Time frame: 24 hours postoperatively
untoward events
eclampsia, drug side effects (over sedation, hypotension, bradycardia)
Time frame: 24 hours postoperatively
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