Study of ALLN-177 in Patients Aged 12 Years or Older With Enteric or Primary Hyperoxaluria and Hyperoxalemia

Inclusion Criteria: 1. Signed a informed consent form or an assent 2. Aged 12 or older with body weight ≥ 35kg 3. History of primary hyperoxaluria or enteric hyperoxaluria associated with a known underlying enteric disorder associated with malabsorption (e.g., bariatric surgery, Crohn's disease, short bowel syndrome, or other malabsorption syndrome) 4. Urinary oxalate ≥ 40mg/24h (normalized for body surface area in children) at Screening in patients with eGFR \>15 mL/min/1.73m2 5. In patients with enteric hyperoxaluria, eGFR \< 45mL/min/1.73m2 at Screening 6. In patients with enteric hyperoxaluria, plasma oxalate \> 5µmol/L at Screening 7. Patients on dialysis, must be stable for greater than 3 months Exclusion Criteria: 1\. Unable or unwilling to discontinue Vitamin C supplementation