Brain Imaging Study of Brain Plasticity in Chronic Stroke Patients

Samsung Medical Center59 enrolled

Overview

In chronic stroke patients, brain network reorganization and recovery mechanism are investigated after stroke onset using functional MRI and diffusion tensor imaging analyses.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Chronic Stroke

Interventions

Chronic strokeOTHER

MRI data acquisition and behavioral test

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * more than 3 months post-stroke * ischemic or hemorrhagic stroke * a person who understands the experiment and has a willingness to participate and signs the agreement Exclusion Criteria: * User of artificial heartbeat * Patients with claustrophobia * Patients with metal implants * Patients who are contraindicated for other common MRI

Locations (1)

Samsung Medical Center

Seoul, South Korea

Outcomes

Primary Outcomes

Correlation coefficient between strength of connection and the Fugl-Meyer Assessment score

Strength of connection is obtained by calculating a correlation coefficient between time courses of both regions in fMRI data.

Time frame: Through study completion, an average of 1 year

Correlation coefficient between the FA value of a tract and the Fugl-Meyer Assessment score

FA value is obtained by assessing a diffusion anisotropy of a specific tract in DTI data.

Time frame: Through study completion, an average of 1 year

Data from ClinicalTrials.gov

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