Study in Chinese Healthy Adults to Evaluate the Safety, Tolerability and Pharmacokinetics on ZSP1601, and the Effect of Food on ZSP1601 Pharmacokinetics

Inclusion Criteria: * Subjects are required to meet the following criteria in order to be included in the trial: 1. Signature of a dated Informed Consent Form (ICF) indicating that the subject has been informed of all the relevant aspects(including adverse events) of the trial prior to enrollment. 2. Subjects must be willing and able to adhere to the visit schedule and protocol requirements and be available to complete the study. 3. Subjects(including partners)have no gestation plans and must use reliable methods of contraception during the study and until 6 months following the last dose of investigational product. 4. Males and female subjects between 18-50 years (Both inclusive). 5. Body weight is no less than 50kg in males and no less than 45kg in females.Body mass index (BMI) 18≤BMI≤28 kg/m2; BMI is determined by the following equation: BMI = weight/height2 (kg/m2). 6. Physical condition:No significant abnormalities in medical history, including cardiovascular system, liver, kidneys, gastrointestinal system, neural system, respiratory system (eg.asthma,asthma induced by exercise,chronic obstructive pulmonary disease), mental, metabolism, etc. 7. Subjects in general good health or No significant abnormalities in the opinion of the investigator as determined by vital signs and a physical examination. Exclusion Criteria: * Eligible subjects must not meet any of the following exclusion criteria: 1. The average daily smoking are more than 5 cigarettes within 3 months prior to screening. 2. Known hypersensitivity and/or allergy to some drugs and food. 3. Known history of drug or alcohol abuse.(defined as consumption of 14 units of alcohol per week:1 unit=285ml of beer; or the equivalent of 25ml of spirit, or 100ml of wine ) 4. Subjects who donated blood or bleeding profusely(\> 400 mL)in the 3 months preceding study screening. 5. Dysphagia or any medical history in gastrointestinal that interferes with the absorption of drugs. 6. History or presence of any disease or condition known to increase the risk of bleeding, eg.acute gastritis, duodenal ulcer, etc. 7. Frequently suffers from postural hypotension. 8. History of frequent nausea or vomit causes by any etiology. 9. Concomitant therapy with any drugs with known hepatic enzyme-inducing or inhibiting agents that may change the activity of CYP3A4 prior to screening or during the study. 10. Use of any prescription or over-the-counter (OTC) medications, vitamins and herbal or dietary supplements within 14 days prior to screening. 11. History of having any special food(including dragon fruit,mango,grapefruit,etc.),strenuous exercises,or other factors may interfere with the absorption, distribution, metabolism, or excretion of drug within 14 days prior to screening. 12. Subjects with recent significant change in diet or exercise . 13. Participated in another clinical research study and received any investigational products within 3 months prior to dosing. 14. Inability to consume the food provided in the study ( a high fat, high calorie meal includes two eggs for 100g, bacon 20g, a butter toast for 50g, french fries for 115g, whole milk for 240ml).This requirement only applies to subjects under fed condition. 15. Presence of clinically significant abnormalities in ECG or QTc\>470ms in males,or QTc\>480ms in females. 16. Pregnancy or breastfeeding at screening and during the study.All female subjects of childbearing potential must have a negative urine pregnancy test at screening and during the trial. 17. Any clinically significant abnormality upon physical examination or in the clinical laboratory tests. History or presence of a clinically significant gastrointestinal, renal, hepatic, neurologic, hematic, endocrine, neoplastic, pulmonary, immune, psychiatric or cardiovascular and cerebrovascular disorder(s) (but not limited to above disorders). 18. Presence of human immunodeficiency virus (HIV), viral hepatitis(including hepatitis C virus (HCV) or hepatitis B virus (HBV) ),treponema pallidum antibodies at screening. 19. Any acute illness or concomitant medication from screening to first dosing. 20. Have chocolate, any food or beverage that contains caffeine or xanthine within 24 hours prior to dosing. 21. Take any product contains alcohol within 24 hours prior to dosing. 22. Positive for urine drug screening or history of substance abuse for a period of 5 consecutive years before screening.