The purpose of this study is to compare between the addition of Mg sulphate or Nalbuphine to intraperitoneal bupivacaine installation in laparoscopic hysterectomy for postoperative pain control and their relative adverse effects.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
80
Patients will receive 30 mL of intraperitoneal bupivacaine 0.25%
Patients will receive intraperitoneal 30 mg/kg of magnesium sulphate.
Patients will receive intraperitoneal 5 mg nalbuphine
Marwa Elbeialy
Cairo, Egypt
Rescue analgesia time
Time to first analgesia requirment(considering the extubation is the zero time)
Time frame: First 24 hours postoperatively
Visual analogue scale [VAS]
Visual analogue scale \[VAS\] will be used to measure pain score at 30 min, 1, 2, 4, 6, 8, 10, 12 and 24 h after surgery. All the study patients will be instructed about the use of the VAS scale before induction of anesthesia (VAS score 0 cm = no pain, VAS score 10 cm = worst possible pain)
Time frame: First 24 hours postoperatively
Total analgesic consumption
Intravenous diclofenac 75 mg will be given as rescue analgesic when VAS ≥ 4.Total diclofenac consumption will be recorded.
Time frame: First 24 hours postoperatively
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