Investigators aimed to compare the restrictive and liberal blood transfusion methods applied in major surgical operations performed in Anesthesiology and Reanimation Clinic and investigate their effects on postoperative transfusion needs, morbidity and mortality.
The test subjects consisted of 892 patients, who belong to ASA (American society of Anesthesiology) I -IV groups, underwent elective major surgery between the 01/01/2016-31/12/2016, and are over the age of 18 years. The demographic data (Age, sex, ASA (American society of Anesthesiology) scors, surgery type) were also recorded. we evaluated the value of Hemoglobin, platelet, APTT (activated partial thromboplastin time), INR (international normalized ratio) preoperatively and postoperatively. In this study, restrictive and liberal blood transfusion groups were investigated.restrictive and liberal transfusion hemoglobin threshold value respectively before perioperative transfusion was 8 g / dL. were defined as restrictive blood transfusion group and perioperative transfusion was over 8 g / dL were defined as liberal blood transfusion group. Adverse events (tachycardia, hypotension, the value of lactate and metabolic acidosis). Postoperatively, the amount of postoperative transfusion unit, duration of hospital stay, requirement of intensive care unit and mortality rate.
Study Type
OBSERVATIONAL
Enrollment
892
hemoglobin threshold value was accepted 8g/dl. restrictive blood transfusion group was defined that if perioperative transfusion was started equal or under hemoglobin level 8 g / dL. Liberal blood transfusion group was defined as perioperative transfusion was started over hemoglobin level 8 g / dL .
University of Health sciences,sisli Hamidiye Etfal Training and Research Hospital
Istanbul, Turkey (Türkiye)
Restrictive or Liberal transfusion
It is determined how many units of RBC (red blood cell ) used during major operations at the hospital in liberal transfusion group or restrictive transfusion group.
Time frame: 52 weeks
Mortality
Survival ratios between the restrictive transfusion group and the liberal transfusion group are compared.
Time frame: 52 weeks
Postoperative transfusion requirement
The requirement of postoperative blood transfusion between the restrictive transfusion group and the liberal transfusion group is determined.
Time frame: 52 Weeks
The Need of ICU
The need of ICU between the restrictive transfusion group and the liberal transfusion group of patients is determined.
Time frame: 52 Weeks
Postoperative Duration of Stay in Hospital of patients
The postoperative duration of stay in hospital of patients between the restrictive transfusion group and the liberal transfusion group are compared.
Time frame: 52 Weeks
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