The study aim is to investigate if preoperative volume bolus based on lean body weight could preserve mean arterial pressure during target controlled infusion of anaesthesia (TCI) or rapid sequence induction of anaesthesia (RSI) in non-cardiac, non-morbidly obese surgery.
40 individuals are enrolled to TCI and RSI groups respectively. The randomization process for preoperative fluid bolus prior to induction of anaesthesia is conducted in respective group at the day of surgery. Preoperative colloid fluid therapy (6 ml/kg LBW, Gelofusine™, Fresenius Kabi Ab, Sweden) is infused rapidly before non-invasive baseline blood pressure (NIBP) measurements in twenty individuals in each group. No other intravenous fluids before induction of anaesthesia. NIBPs, pulse frequency, peripheral saturation (SpO2) are registered and collected 20 minutes post induction.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Enrollment
80
Preoperative colloid fluid bolus 6ml/kg ideal body weight
Sunderby hospital
Luleå, Sweden
Incidence of blood pressure drops
blood pressure drop below mean arterial pressure at 65 mmHg during anesthesia induction
Time frame: 20 minutes post anesthesia induction
Effect of preoperative fluid bolus
Does preoperative fluid bolus decrease incidence of blood pressure drops
Time frame: 20 minutes post anesthesia induction
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