Fentanyl is analgesia medication. There has not pain nerve in the lung. Flexible bronchoscopy(FB) is used in the respiratory medicine. So people will not feel pain in the process of FB. The purpose of the study is to know if Fentanyl is useful in the conscious sedation of FB.
Fentanyl is opioid receptor agonists. It is a fast-acting, short duration and potent analgesics. Flexible bronchoscopy (FB) is mostly used in the diagnosis and therapy in the respiratory disease. As we know, there has not pain nerve in the lung. People will not feel pain when they are in FB. If fentanyl will be effective in FB? Our study will observe the effect of conscious sedation in FB with fentanyl or without fentanyl.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
500
Five minutes before the patients is done the flexible bronchoscopy, fentanyl will be intravenous injected.
Five minutes before the patients is done the flexible bronchoscopy, midazolam will be intravenous injected.
Propofol will be intravenous injected as soon as the flexible bronchoscopy begins.
perioperative changes of blood pressure
For each patient,bispectral index monitoring after anesthesia. Bp will be measured.
Time frame: every 5 minutes from the operation beginning to end
perioperative time
For each patient, record the time bronchoscopy in and out
Time frame: from the operation beginning to end
Adverse events
For each patient, Adverse events (overall intraoperative cough,bleeding,low oxygen solution) will be record in the operation
Time frame: in the process of the operation
Patient satisfaction rate
One day after the patient do the bronchoscopy, ask him/her about the satisfaction to the operation
Time frame: One day after the operation
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Bispectral Index monitoring will be used in the process of the flexible bronchoscopy.