This is an intersectional and interdisciplinary screening program in Viborg Municipality, including 67 years old citizens. This observational study will estimate the cost-effectiveness of a combined screening program for the following conditions: Abdominal aortic aneurysm, peripheral arterial disease, carotid plaque, hypertension, arrhythmia, and type-2-diabetes. Furthermore, the incidence of the outlined conditions will be described and so will the result of the intervention initiated (secondary medical prophylaxis, smoking cessation, introduction to nutritionally deficient diet etc.)
Description of the cohort: All Viborg municipality citizen are invited to the combined screening program around there 67th birthday. Participants with positive screening results are offered following up consultations and prophylactic interventions are initiated (secondary medical prophylaxis, smoking cessation, introduction to nutritionally deficient diet etc.) 67 years-old citizens from the surrounding municipalities without the offer of the combined screening are used as a control group (1 case: 5 controls). There are no exclusion criteria. The screening examination includes: Blood pressure in both arms, ankle brachial blood pressure index (ABI), ultrasound for carotid plaque and abdominal aortic aneurysm, HbA1c and pulmonary function test. Furthermore, a questionnaire on lifestyle parameters, BMI, medical history, walking-related pain and self-rated quality of life (EQ-5D). One year after the screening examination, the participants will receive a questionnaire in order to evaluate the effect from a participant perspective. The cost(-effectiveness) of the screening program will be estimated after 5 years based on prevalence of diseases, response rate, data extraction from nationwide registries and existing evidence of disease prevention.
Study Type
OBSERVATIONAL
Enrollment
4,500
Cardiovascular research Center (KVC), Viborg Hospital
Viborg, Denmark
Baseline prevalence of peripheral arterial disease (PAD) in men and women aged 67 years from a population screening study on the Municipal of Viborg.
Ankel Brachial Index
Time frame: Inclusion will take place from sep. 2014 to sep. 2020
Baseline prevalence of abdominal aortic aneurysm (AAA)
Ultra sound examination (AP diameter (mm))
Time frame: Inclusion will take place from sep. 2014 to sep. 2020
Baseline prevalence of diabetes
Bedside HbA1c
Time frame: Inclusion will take place from sep. 2014 to sep. 2020
Baseline prevalence of hypertension
BP(mmhg)
Time frame: Inclusion will take place from sep. 2014 to sep. 2020
Baseline prevalence of cardiac arrythmia
ECG
Time frame: Inclusion will take place from sep. 2014 to sep. 2020
Baseline prevalence of carotic plaques
Ultra sound examination of A. carotis (IMT in mm)
Time frame: Inclusion will take place from sep. 2014 to sep. 2020
The cost(-effectiveness) of the screening program
Socio-economic evaluation (national register data), QALY
Time frame: 5 years after ending inclusion
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