Stability of the Microbiome in IBD and IBS

Inclusion Criteria: * patients with inflammatory bowel disease and irritable bowel syndrome and stable therapy since three months * patients with the indication for colonoscopy Exclusion Criteria: * age under 18 * pregnancy * new therapy planned * change of therapy within the last three months * acute exacerbation of the inflammatory bowel disease * colon pathologies of other origin: colocarcinoma, Illnesses with diarrhea (f.e.microscopic colitis), short bowel syndrome, malabsorption, colectomy * intake of antibiotics in the last three months * intake of probiotics in the last month * intake of antibiotics or probiotics during the study * new proton pump inhibitor therapy * significant change of nutrition in the last three months * holidays outside europe in the last month * gastroenteritis in the last three months * intake of laxatives * nonsteroidal antiinflammatory drugs should be avoided and documented