The Relationship Between Salt Restriction and Taste Sensitivity in Patients With Chronic Kidney Disease

N/AWithdrawnNCT03397550

Peking University First Hospital

Overview

The compliance of salt restriction in patients with CKD may be associated with taste sensitivity.

Study Type

OBSERVATIONAL

Conditions

Renal Insufficiency, Chronic Chronic Kidney Diseases

Interventions

salt restriction educationOTHER

Salt intake target：\<5g/d Method：the standard salt restriction education will be lasting for 10-15 minutes by oral explanation at baseline.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * stage 3-5 CKD patients * clinical stable Exclusion Criteria: * renal replacement therapy * cancer * systemic infection * Alzheimer's disease * acute cardiovascular events, active hepatitis * all other study-obstructive conditions

Locations (1)

Peking University First Hospital

Beijing, China

Outcomes

Primary Outcomes

ratings of taste sensitivity assessed by the ISO method of investigating sensitivity of taste（ISO 3972:1991）

Taste sensitivity is measured by five taste solutions（salty、sour、bitter、sweet、umami). Every taste solution contains 8 different concentration. Detection , recognition and difference thresholds will be measured .Their definitions are as bellow. Detection threshold：minimum value of sensory stimulus needed to give rise to a sensation. The sensation need not be identified. Recognition threshold：minimum value of a sensory stimulus permitting identification of the sensation perceived. Difference threshold：value of the smallest perceptible difference in the physical intensity of a stimulus.

Time frame: up to 12 weeks after intervention

Data from ClinicalTrials.gov

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