This study will evaluate the bioavailability between the veliparib tablet formulation to the capsule formulation; and will assess the effect of food on veliparib bioavailability in participants with ovarian cancer.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Maximum observed plasma concentration (Cmax)
Maximum observed plasma concentration (Cmax)
Time frame: Up to approximately 8 days after initial dose of study drug
Time to Maximum Observed Plasma Concentration (Tmax)
Time to maximum observed plasma concentration (Tmax).
Time frame: Up to approximately 8 days after initial dose of study drug
Apparent Terminal Phase Elimination Rate Constant (β or Beta)
Apparent terminal phase elimination rate constant (β or Beta).
Time frame: Up to approximately 8 days after initial dose of study drug
Terminal Phase Elimination Half-life (t1/2)
Terminal phase elimination half-life (t1/2)
Time frame: Up to approximately 8 days after initial dose of study drug
Area Under the Plasma Concentration-time Curve (AUC) from Time 0 to Time of the Last Measurable Concentration (AUCt)
Area under the plasma concentration-time curve (AUC) from time 0 to time of the last measurable concentration (AUCt).
Time frame: Up to approximately 8 days after initial dose of study drug
AUC from time 0 to infinite time (AUC∞)
AUC from time 0 to infinite time (AUC∞)
Time frame: Up to approximately 8 days after initial dose of study drug
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Intravenous