ReFlow Medical Wingman Catheter Wing-IT Clinical Trial

Inclusion Criteria: * Patient is willing and able to provide informed consent. * Patient is willing and able to comply with the study protocol. * Patient is \> 18 years old. * Patient has peripheral arterial disease requiring revascularization as evidenced by contrast, CT or MR angiography. * Patient has at least one but not more than two occluded infrainguinal arteries that are 99-100% stenosed and no flow is observed in the distal lesion except the flow from collateral circulation. * Target lesion(s) is ≥ 1 cm and \< 30 cm in length by visual estimate. * Target vessel is ≥ 2.0 mm in diameter. * Patient has Rutherford Classification of 2-5. * Lesion cannot be crossed by concurrent conventional guidewire. * Reconstitution of vessel at least 2cm above bifurcation/trifurcation. * Occlusion can be within previously implanted stent. Exclusion Criteria: * Patient has a known sensitivity or allergy to contrast materials that cannot be adequately pre-treated. * Patient has a known sensitivity or allergy to all anti-platelet medications. * Patient is pregnant or lactating. * Patient has a co-existing disease or medical condition contraindicating percutaneous intervention. * Target lesion is in a bypass graft. * Patient has had a failed crossing attempt without an intervening intervention on the target limb within the past 14 days. * Patient has a planned surgical or interventional procedure within 30 days after the study procedure.