Cardiovascular Clinical Project to Evaluate the Regenerative Capacity of CardioCell in Patients With Acute Myocardial Infarction (AMI)

Inclusion Criteria: * Acute myocardial infarction successfully treated by infarct related artery (IRA) successful revascularization * Male and female patients, aged 18-80 years * Large myocardial injury as demonstrated by LVEF ≤45% and/or infarct size (IS) ≥10% of the LV muscle on cMRI 2-5 days after pPCI * Signed informed consent Exclusion Criteria: * Pacemaker or other contraindications to cardiac MRI * Malignancy * Moderate or severe immunodeficiency * Acute or chronic bacterial or viral infectious disease * Soft tissue disease or local infection in a place of required artery puncture * Pregnancy or breastfeeding * Any objective or subjective reason for inability to attend follow-up visits * Females of childbearing potential, who does not want to use a highly effective method of contraception * Females of childbearing potential who does not have a menstrual period confirmed and a negative highly sensitive urine or serum pregnancy test * Participation in any other clinical research study that has not reached the primary efficacy endpoint or otherwise would interfere with the patient's participation in this project * Life expectancy \< 1 year * Any concurrent disease or condition that, in the opinion of the investigator, would make the patient unsuitable for participation in the project