The main purpose of this study is to compare the effects of high intensity interval training and moderate intensity continuous training on inflammatory profile and metabolic markers, after 8 weeks of intervention trial in obese women.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
48
no counseling or nutritional therapy and no exercise
no counseling or nutritional therapy. 8 weeks of individualized and supervised ergometer-based moderate continuous intensity training (MICT).
no counseling or nutritional therapy. 8 weeks of individualized and supervised ergometer-based high intensity interval training (HIIT)
Inflammatory profile
C-reactive protein (CRP) (mg/dL)
Time frame: 8 weeks (baseline to 8 week follow-up assessment)
Inflammatory profile
Interleukin 6 (IL-6) (ng/mL)
Time frame: 8 weeks (baseline to 8 week follow-up assessment)
Inflammatory profile
Interleukin 10 (IL-10) pg/mL, Interleukin-1B (IL-1B) pg/mL, Tumor Necrosis Factor (TNF)-α (pg/mL), Adiponectin (pg/mL), Monocyte chemoattractant protein 1 (MCP-1) (pg/mL), Leptin (pg/mL)
Time frame: 8 weeks (baseline to 8 week follow-up assessment)
Body Composition and Anthropometric profile
Body weight (kg), Fat free mass (FFM) (kg), fat mass (FM) (kg)
Time frame: 8 weeks (baseline to 8 week follow-up assessment) ]
Body Composition and Anthropometric profile
Body Mass Index (BMI) (kg/m²)
Time frame: 8 weeks (baseline to 8 week follow-up assessment) ]
Body Composition and Anthropometric profile
Waist circumference (cm), hip circumference (cm)
Time frame: 8 weeks (baseline to 8 week follow-up assessment) ]
Body Composition and Anthropometric profile
Body Adiposity Index (BAI) and Waist-To-Hip Ratio (WHR)
Time frame: 8 weeks (baseline to 8 week follow-up assessment) ]
Insulin sensitivity
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Insulin sensitivity was estimated using homeostasis model assessment index (HOMA)
Time frame: 8 weeks (baseline to 8 week follow-up assessment) ]
Lipid profile
Lipid profile was assessed by measuring levels of triglyceride (TG) (mg/dL), total cholesterol (CT) (mg/dL), high-density lipoprotein cholesterol (HDL-C) (mg/dL) and low-density lipoprotein cholesterol (LDL-C) (mg/dL)
Time frame: 8 weeks (baseline to 8 week follow-up assessment) ]
Cardiorespiratory Fitness (CRF)
CRF was assessed by measuring Peak Oxygen uptake (VO2peak) mL/kg/min
Time frame: 8 weeks (baseline to 8 week follow-up assessment) ]
Blood Pressure (BP)
Blood Pressure (mmHg) was assessed by measuring rest levels of Systolic blood pressure (SBP) and Diastolic blood pressure (DBP)
Time frame: 8 weeks (baseline to 8 week follow-up assessment) ]
Resting Energy Expenditure (REE)
Resting Energy Expenditure (kcal/day) was measured through indirect calorimetry with an open-circuit ventilated-hood system Substrate oxidation rate was calculated from VO2 (mL/min) and VCO2 (mL/min)
Time frame: 8 weeks (baseline to 8 week follow-up assessment) ]
Substrate oxidation rate
Substrate oxidation rate was calculated from VO2 (mL/min) and VCO2 (mL/min)
Time frame: 8 weeks (baseline to 8 week follow-up assessment) ]