Supplementation Trial on Arginine With Metabolic Profiling

Inclusion Criteria: * BMI 18.5 - 25 kg/m2. * Must be physically active (exercise at least 2 days/week). * Willing to refrain from alcohol and supplements for the duration of the study. * Willing to refrain from supplement ingestion, nuts, watermelon, and cracklins (fatback) for the 2 weeks prior to the initial treatment diet through the duration of the study. Exclusion Criteria: * HIV or AIDS * Uncontrolled CVD/arrhythmia * Type I or type II diabetes * Pregnancy (or breastfeeding) * Diagnosed eating disorder * Non-normal sleeping patterns * Chronic neurological condition * Altered metabolism including growth hormone disorders * Use of nicotine or tobacco products * Heavy caffeine use (≥ 350 mg caffeine/d) * Whole blood donation within previous eight weeks * Protein supplementation * Protein wasting disease. * Exclusionary medications include diuretics, beta-blockers, weight loss medications or diet pills, anti-inflammatory drugs (corticosteroid/ anabolic steroid/NSAID), antipsychotic medication or other medication that may affect fluid balance, metabolism, or body weight. * Prisoners and adults who are unable to consent will be excluded from the study. * Lastly any other medical, psychiatric, or behavioral factors in the judgement of the Principle Investigator that may interfere with study participation or the ability to follow the protocol.