Nausea and vomiting after general anesthesia is one of the common anesthetic complications. If the patient is discharged from the hospital after surgery, proper treatment may be delayed or impossible if nausea or vomiting occurs. Thus, It is necessary to prevent these symptoms beforehand. Patients who underwent gynecologic surgery will be treated with prophylactic ramosetron to determine whether the frequency of nausea and vomiting is decreased when the patient returned home after discharge.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Enrollment
100
Ramosetron 0.3 mg is administered after induction of general anesthesia.
Normal saline 2 ml is administered after induction of general anesthesia.
Seoul National Univ. Bundang Hospital
Seongnam-si, Gyeonggi-do, South Korea
RECRUITINGThe change in the occurrence of postoperative nausea
Time frame: Postoperative 30 minute, 3 hour, 24 hour, and 48 hour
The change in the occurrence of postoperative vomiting
Time frame: Postoperative 30 minute, 3 hour, 24 hour, and 48 hour
The change of postoperative pain score
Score range is from 0 to 10.
Time frame: Postoperative 30 minute, 3 hour, 24 hour, and 48 hour
The change in the number of postoperative administration of rescue analgesic drug
Time frame: Postoperative 30 minute and 3 hour
The change in the number of postoperative administration of rescue antiemetic drug
Time frame: Postoperative 30 minute and 3 hour
The change of patient's satisfaction score
Score range is from 0 to 10.
Time frame: Postoperative 30 minute, 3 hour, 24 hour, and 48 hour
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