The goal of this trial is to examine long-term effects of laparoscopic gastric bypass (LRYGB) and sleeve gastrectomy (LSG) on bone mineral density, fracture risk, and body composition ≥ 5 years post-surgery.
Bariatric surgery shows impressive results in terms of weight loss and resolution of comorbidities. Still, there are questions as to the frequency of long-term adverse effects: data on alterations in bone health are missing, The goal of this trial is to examine long-term effects of laparoscopic gastric bypass (LRYGB) and sleeve gastrectomy (LSG) on bone mineral density, fracture risk, and body composition ≥ 5 years post-surgery.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
140
measurement of vertebral bone and hip bone mineral density
St Claraspital
Basel, Switzerland
Total hip T-Score measured with dual-energy x-ray absorptiometry
measured score will be compared to reference score for this age
Time frame: 5-7 years after bariatric surgery
Total vertebral T-Score measured with dual-energy x-ray absorptiometry
measured score will be compared to reference score for this age
Time frame: 5-7 years after bariatric surgery
fracture risk assessed by FRAX score
measured score will be compared to reference score for this age
Time frame: 5-7 years after bariatric surgery
plasma concentration of C-terminal telopeptide (CTX)
measured plasma concentration will be compared to reference for this age
Time frame: 5-7 years after bariatric surgery
plasma concentration of vitamin D3
measured plasma concentration will be compared to reference for this age
Time frame: 5-7 years after bariatric surgery
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