Opioid analgesics have many side effects. Quadratus lumborum (QL) block is one kind of regional nerve block that can reduce the side effects of opioid analgesics. The investigators hypothesize that QL block with local analgesics (ropivacaine) can significantly reduce pain intensity in comparison with placebo.
Opioid analgesics have been used to control the pain. However, many postoperative complication, such as nausea, vomiting, constipation, ileus, etc are related to opioid usage. Recently, local or regional pain nerve block, such as transversus abdominis plane block, wound infiltration, have been reported in several studies. Quadratus lumborum (QL) block was first introduced in the abstract of 2007 European Society of Regional Anesthesia. The effect is longer and more than that of transversus abdominis plane block because it works close to the spinal cord nerves. The QL block can be an effective pain control method for patients who underwent ileostomy closure. The aim of this study is to compare pain intensity after ileostomy closure between QL block (ropivacaine) group and placebo group (normal saline).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
57
After general anesthesia, an anesthesiologist will perform an quadratus lumborum block with 0.75% ropivacaine (20cc) under ultrasound guidance.
After general anesthesia, an anesthesiologist will perform an quadratus lumborum block with normal saline (20cc) under ultrasound guidance.
Kyungpook National University Chilgok Hospital
Daegu, South Korea
Pain numerical rating scale (NRS)
1. Pain NRS during rest and cough 2. NRS scale 0-10:0, "no pain"; 10, "worst pain imaginable"
Time frame: 6 hours after surgery
Pain NRS
1. Pain NRS during rest and cough 2. NRS scale 0-10:0, "no pain"; 10, "worst pain imaginable"
Time frame: 2, 12,24,36,48,72 hour after surgery
Rescue opioid analgesic requirement
Overall postoperative rescue of opioid analgesic requirement described by using the Defined Daily Dose
Time frame: postoperative day 0,1,2,3
Postoperative nausea and vomiting scale
Postoperative nausea and vomiting scores (assessed using a 0-2 categorical scale; no nausea/nausea/vomiting)
Time frame: 2, 12,24,36,48,72 hour after surgery
Occurrence of prolonged post-operative ileus
Occurrence of prolonged post-operative ileus (assessed using a 0-1 categorical scale; no ileus/ ileus)
Time frame: 8 weeks after surgery
Time to first oral fluid intake
Time to first oral fluid intake after surgery
Time frame: 8 weeks after surgery
Time to first oral soft diet
Time to first oral soft diet after surgery
Time frame: 8 weeks after surgery
Length of hospital stay
Length of hospital stay after admission
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Time frame: 8 weeks after surgery