The investigators will monitor for the incidence of adverse-events in a prospective, longitudinal, non-interventional and observational real-world sub-study of adults patients with moderate-to-severe AD who are receiving dupilumab as standard-of-care therapy.
The investigators will conduct a prospective, longitudinal, non-interventional and observational sub-study of patients receiving dupilumab as normal standard-of-care treatment to assess the efficacy (Specific Aim #1) and safety (Specific Aim #2) of dupilumab for the treatment of moderate-to-severe AD, as well as the prevention and/or mitigation of comorbid health conditions (Specific Aim #3). This study will address the hypotheses that dupilumab will lead to improved long-term control and decreased severity of AD, and that long-term monitoring will shed light on the incidence of adverse drug events.
Study Type
OBSERVATIONAL
Enrollment
46
Biologic (monoclonal antibody)
Northwestern University Department of Dermatology
Chicago, Illinois, United States
Quantified Itch Survey
Time frame: 1 to 3 months
Quantified Sleep Survey
Time frame: 1 to 3 months
Quantified Quality of Life Survey
Time frame: 1 to 3 months
Occurrence of any AEs by 24 months
Will be determined based off of patient reported safety events
Time frame: 24 months
Occurrence of any infections by 24 months
Will be determined based off of patient reported safety events
Time frame: 24 months
Occurrence of any SAEs by 24 months
Will be determined based off of patient reported safety events
Time frame: 24 months
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