Effects of Oxymizer Pendant Cannula Versus Conventional Nasal Cannula During Endurance Shuttle Walk Tests in Hypoxemic Patients With Idiopathic Pulmonary Fibrosis

Klaus Kenn22 enrolled

Overview

Aim of this study is to investigate the effects of an Oxymizer pendant nasal cannula in hypoxemic patients with idiopathic pulmonary fibrosis during walking.

Patients will be recruited during an inpatient pulmonary rehabilitation program. They will perform three shuttle walk tests on three consecutive days (see below). While performing those tests, the patient's prescribed oxygen flow rate is applicated either through the conventional nasal cannula (CNC) or the Oxymizer.On the first day, patients perform an incremental shuttle walk test to determine maximum walking speed using a conventional nasal cannula. On two consecutive days, patients will perform two endurance shuttle walk tests at 85% of the maximum incremental shuttle walk test speed. Supplemental oxygen will be provided via nasal cannula at the prescribed oxygen flow rate. Patients will be randomly assigned to perform one test with the Oxymizer and the other one with a conventional nasal cannula.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Idiopathic Pulmonary Fibrosis Hypoxemia

Interventions

Oxymizer® pendant nasal cannulaDEVICE

Supplemental oxygen is provided by an Oxymizer pendant nasal cannula.

conventional nasal cannulaDEVICE

Supplemental oxygen is provided by a conventional nasal cannula.

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * firmed diagnosis of idiopathic pulmonary fibrosis * indication for supplemental oxygen therapy during exercise * referred to an inpatient rehabilitation program at the Schön Klinik Berchtesgadener Land Exclusion Criteria: * cardiovascular diseases that influence the patient's physical performance * orthopedic comorbidities that prevent the patient from performing an incremental or endurance shuttle walk test * carbon dioxide pressure above 45 mmHg at rest and ambient air

Locations (1)

Schön Klinik Berchtesgadener Land

Schönau am Königssee, Germany

Outcomes

Primary Outcomes

Endurance shuttle walk test distance

Distance patients walk during an endurance shuttle walk test

Time frame: at baseline, at isotime of endurance shuttle walk test and at the end (maximum 20 min) of endurance shuttle walk test

Secondary Outcomes

oxygen saturation

measured by Sentec Digital Monitoring System

Time frame: at baseline, at isotime of endurance shuttle walk test and at the end (maximum 20 min) of endurance shuttle walk test

heart rate

measured by Sentec Digital Monitoring System

Time frame: at baseline, at isotime of endurance shuttle walk test and at the end (maximum 20 min) of endurance shuttle walk test

breathing frequency

measured by NoxT3 device

Time frame: at baseline, at isotime of endurance shuttle walk test and at the end (maximal 20 min) of endurance shuttle walk test

carbon dioxide pressure

transcutaneously carbon dioxide pressure measured by Sentec Digital Monitoring System

Time frame: at baseline, at isotime of endurance shuttle walk test and at the end (maximum 20 min) of endurance shuttle walk test

time to desaturation

time (seconds) is measured until oxygen saturation drops below 90% or 85 % respectively

Time frame: From beginning of endurance shuttle walk test until the oxygen saturation reaches defined thresholds, or ESWT reaches maximum time frame of 20 minutes

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.