Preemptive Analgesic Effects of Rectus Sheath Block in Laparoscopic Cholecystectomy Patients

Asan Medical Center200 enrolled

Overview

The purpose of this study was to investigate the effectiveness of preemptive effect of rectus sheath block (RSB) and intercostal nerve block (ICNB) on postoperative visceral pain in laparoscopic cholecystectomy (LLC). After induction of general anesthesia, group of patient is decided randomly. In Group pre, RSB and ICNB are performed with 0.25% Ropivacaine 40ml before the operation. In Group post, RSB and ICNB are performed with 0.25% Ropivacaine 40ml after the operation. Measure the NRS and compare the rescue analgesic dose used at 0, 0.5, 1, 2, 6, 9, 18, and 24 hours after arrival at the recovery room.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

TRIPLE

Enrollment

200

Conditions

Preemptive Peripheral Nerve Block Pain, Postoperative Acute Pain

Interventions

Eligibility

Sex: ALLMin age: 20 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. adults between the ages of 20 and 80 2. scheduled laparoscopic cholecystectomy patient 3. ASA class 1 or 2 4. Patients who have voluntarily agreed in writing to participate in the trial Exclusion Criteria: 1. Patient with side effects on local anesthetics or steroids 2. Patient who are taboo of peripheral nerve block such as blood clotting disorder, infection, etc. 3. Patients with uncontrolled medical or psychiatric problem 4. Patient does not agree to participate in the study 5. Patients who are pregnant or lactating 6. Patients whose visceral pain is expected to be too severe 7. Patients receiving a single laparoscopic cholecystectomy (including using a robot)

Outcomes

Primary Outcomes

Difference of analgesic consumption between both group

The difference in analgesics usage between the two groups after the operation is checked at fixed intervals (at 0, 0.5, 1, 2, 6, 9, 18, 24 hours after operation) to compare.

Time frame: at 0, 0.5, 1, 2, 6, 9, 18, 24 hours after operation

Secondary Outcomes

compare the Numeric rating scale (NRS)

The Numeric Rating Scale (NRS-11) is an 11-point scale for patient self-reporting of pain. It is for adults and children 10 years old or older. 0: No pain, 1-3: mild pain, 4-6: Moderate pain, 7-10: severe pain, 10: worst pain imaginable. After surgery, the NRS differences between the two groups were compared at a constant interval (0, 0.5, 1, 2, 6, 9, 18, 24 hours postoperatively).