Unexplained Early Miscarriage : Role and Prevalence of Lower Genital Tract Infections

Cairo University1,850 enrolled

Overview

The study group included 910 women who attended Fayoum university hospital gynecology outpatient clinic for postabortive evaluation. The control group included 940 women attended outpatient clinic for any other procedure or complaint all patients were screened by serum samples to detect IgM / IgG to Chlamydia trachomatis (DRG Chlamydia Trachomatis IgM / IgG Enzyme immunoassay) and by high vaginal and Endocrvical swabs for bacterial, protozoal and chlamydial infection- examined by PCR- (from +ve samples to chlamydial IgM / IgG).

Study Type

OBSERVATIONAL

Enrollment

1,850

Conditions

First Trimester Abortion

Interventions

vaginal swabPROCEDURE

high vaginal and Endocrvical swabs for bacterial, protozoal and chlamydial infection- examined by PCR

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 40 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * The Study group included Women with recent unexplained early miscarriage (pregnancy duration 12 weeks or less and miscarriage within 4 weeks) * The control group included Women with any other gynecological complaint or in need of family planning Exclusion Criteria: * Miscarriage of Pregnancy duration more than 12 ws Documented causes of miscarriage as fetal or uterine anomalies, antiphospholipid syndrome, endocrine factors….etc * Recent antibiotic, antifungal or antiprotozoal treatment

Locations (1)

Kasr Alainy medical school

Cairo, Egypt

Outcomes

Primary Outcomes

prevalence of lower genital tract infection

candida, bacterial vaginosis , trichomonas , mycoplasmal or chlamydial infection

Time frame: At time of examination

Data from ClinicalTrials.gov

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