This study aims to compare the effects of transcranial direct current stimulation on the clinical and cognitive function in patients with chronic migraine.
The patients will be randomized into 1 of 3 groups: active tDCS for 15 minutes, active tDCS for 15 minutes, with an interval of 20 minutes and more 15 minutes os stimulation, sham tDCS for 15 minutes. The tDCS will be applied for 10 days over 2 weeks.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
31
Transcranial Current Stimulation equipment consists of an ammeter (measured with current intensity), a potentiometer (voltage controller between the electrodes), a generator (two 9-volt batteries) and two electrodes (anode and cathode). The direct low-amplitude currents released by the electrodes reach the cortex and modify the neuronal potentials.
Federal University of Paraiba
João Pessoa, Paraíba, Brazil
Migraine Disability Assessment - MIDAS
Change in perform activities of daily living associate to migraine assessed on the Migraine Disability Assessment - MIDAS.
Time frame: "before treatment", "after treatment - up to 2 weeks " and "up to 1 month after the last day of treatment"
Headache Impact Test - HIT-6
Change in quality of life associate to migraine assessed on the Headache Impact Test-6 (HIT-6)
Time frame: "before treatment", "after treatment - up to 2 weeks " and "up to 1 month after the last day of treatment"
Wechsler Intelligence Scale Letters
Change in cognitive ability assessed on the Wechsler Adult Intelligence Scale Letters
Time frame: "before treatment", "after treatment - up to 2 weeks " and "up to 1 month after the last day of treatment"
Wechsler Intelligence Scale Numbers Test
Change in cognitive ability assessed on the Wechsler Adult Intelligence Scale Numbers Test
Time frame: "before treatment", "after treatment - up to 2 weeks " and "up to 1 month after the last day of treatment"
Hayling's Test Hayling's Test
Change in operational memory assessed on the Hayling's Test Evaluate operational memory
Time frame: "before treatment", "after treatment - up to 2 weeks " and "up to 1 month after the last day of treatment"
Trail Making Test part B
Change in executive functions assessed on the Trail Making Test part B
Time frame: "before treatment", "after treatment - up to 2 weeks " and "up to 1 month after the last day of treatment"
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Salthouse Visual Patterns and Lyrics
Change in visual processing speed assessed on the Salthouse Visual Patterns and Lyrics
Time frame: "before treatment", "after treatment - up to 2 weeks " and "up to 1 month after the last day of treatment"
Nine Hole Peg Test
Change in the motor processing speed assessed on the Nine Hole Peg Test
Time frame: "before treatment", "after treatment - up to 2 weeks " and "up to 1 month after the last day of treatment"
Paced Auditory Serial Addition Task
Change in selective attention assessed on the Paced Auditory Serial Addition Task
Time frame: "before treatment", "after treatment - up to 2 weeks " and "up to 1 month after the last day of treatment"
Concentrated Attention Test
Change in selective attention assessed on the Concentrated Attention Test
Time frame: "before treatment", "after treatment - up to 2 weeks " and "up to 1 month after the last day of treatment"
Visual Attention Test (Attention Matrices)
Change in selective attention assessed on the Visual Attention Test (Attention Matrices)
Time frame: "before treatment", "after treatment - up to 2 weeks " and "up to 1 month after the last day of treatment"
Montreal Cognitive Assessment
Change in cognition assessed on the Montreal Cognitive Assessment
Time frame: "before treatment", "after treatment - up to 2 weeks " and "up to 1 month after the last day of treatment"
Side Effects Questionnaire
adverse effects assessment
Time frame: "every day for up to 2 weeks"