Safety, Performance and Durability of the TIES® Implant in Patients Requiring a Permanent Ileostomy

Inclusion Criteria: * Subject has ulcerative colitis, familial adenomatous polyposis coli or other diseases such as Crohn´s disease for whom a permanent ileostomy is indicated; or the subject has a medical need for an alternative to an existing conventional end-ileostomy, continent ileostomy or pelvic pouch; and * Patient is a male ≥18 years of age or female ≥18 years of age (See exclusion criterion 4 regarding female with childbearing potential); and * Signed written informed consent has been obtained prior to any study- related procedure. Exclusion Criteria: * Concurrent gastrointestinal fistula, parastomal or incisional hernia, or a history of recurrent gastrointestinal fistula, recurrent parastomal hernia(s), and/or recurrent incisional hernia(s). * Patients with undetermined colitis. * An acute episode of Crohn´s disease occurring during the last three months before the operation * Females who are of childbearing potential and do not wish to use birth control measures for the duration of the study * Patients receiving immunosuppressives, oncologic treatment or anticoagulants. * Any clinically significant, abnormal, baseline laboratory result which in the opinion of the surgeon, affects the patient's suitability for the study or puts the patient at risk if he/she undergoes surgery * Severe illness which, in the opinion of the surgeon may put the patient at risk when participating in the study or may affect the patient's ability to complete the study visits * Condition associated with the risk of poor protocol compliance, e.g. alcoholism and/or drug abuse, dementia, self-destructive personality disorder * Subjects with BMI ≤ 17 kg/m2 or BMI ≥ 33 kg/m2 * Participate in other clinical studies that could interfere with the result in the ongoing study