Older HIV-infected Adults and Drug Interactions: French Cross-sectional Study

University Hospital, Caen13,225 enrolled

Overview

Drug interactions between antiretroviral drugs and concomitants drugs and between antiretroviral need to be studied HIV-population is ageing. The referential of interactions is the Liverpool base.

Filters in the French social security system database, 2016 : * Code of Pathology "Human Immunodeficiency Virus (HIV) infection" Age ≥ 65 years * Treatment with an antiretroviral between January 1, 2016 and December 31, 2016

Study Type

OBSERVATIONAL

Enrollment

13,225

Conditions

HIV Infections

Eligibility

Sex: ALLMin age: 66 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Men and women over than 65 years with an HIV infection and insured at the French Primary Health Insurance fund No exclusion Criteria

Outcomes

Primary Outcomes

frequency of major drug-drug interactions

MDDI between 2 drugs (ARV/ARV or ARV/non-ARV) delivered during the same period yielding to a "Do Not Coadminister" statement, according to the University of Liverpool website (www.hiv-druginteractions.org/checker).

Time frame: between Jan, 1st 2016 and Dec, 31st 2016

Secondary Outcomes

costs associated with major drug-drug interactions

The costs were defined as all reimbursed healthcare acts recorded in the SNIIRAM

Time frame: during 2016

Data from ClinicalTrials.gov

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