Argus II Retinal Prosthesis System - Better Vision RP Study

Inclusion Criteria: * Adults, age 25 years or older; * Diagnosed with advanced Retinitis Pigmentosa (including syndromic RP), Choroideremia, Leber's Congenital Amaurosis, or Rod-Cone disease; * A measurable central residual visual field of 5° radius or smaller in both eyes, as determined by Goldmann perimetry; * Visual acuity of 0.1 (1.0 logMAR) or worse in the eye to be implanted, as measured by ETDRS chart; * Previous history of useful form vision; * Provided written, informed consent to participate in the study. Exclusion Criteria: * Ocular diseases or conditions that could prevent the Argus II implant from working (e.g., optic nerve disease, central retinal artery or vein occlusion, history of retinal detachment, trauma, etc.); * Ocular structures or conditions that could prevent the successful implantation of the Argus II Implant or adequate healing from surgery (e.g. extremely thin conjunctiva; axial length \<20.5 mm or \> 26 mm; corneal ulcers; choroidal neovascularization in the area of the intended tack location, etc.); * Pre-disposition to eye rubbing; * Any disease or condition that prevents understanding or communication of informed consent, study demands, and testing protocols, including: 1. cognitive decline including diagnosed forms of dementia and/or progressive neurologic disease, 2. psychiatric disease including diagnosed forms of depression; 3. does not speak a principal language associated with the region, and 4. deafness or selective frequency hearing loss that prevents hearing device alarms and alerts; * Pregnant or wish to become pregnant during the course of the study; * Participating in another investigational drug or device study that may conflict with the objectives, follow-up, or testing of this study; * Inability to tolerate general anaesthesia or the recommended antibiotic and steroid regimen associated with the implantation surgery; * Conditions likely to limit life to less than 1 year from the time of inclusion.