While they are documented in patients in remission of testicular cancer, the sequelae of chemotherapy and the impact of the disease and its treatments on the living conditions and QoL of women in remission of rare ovarian cancer remain poorly explored. The coordinator therefore propose a national 2-step case-control study to evaluate 1) chronic fatigue and QoL and 2) chemotherapy-related sequelae in adult patients in remission of surgery-treated TGMO or TSCS (conservative or not) supplemented with chemotherapy
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
OTHER
Masking
NONE
Enrollment
268
Patients will complete self-questionnaires of living conditions and quality of life (MFI-20, FACT-G/FACT-O, FACT/COG-NTX, FACT-Cog, HADS, Insomnia Severity Index , International Physical Activity Questionnaire)
Patients will perform : * Cardiac assesments (ECG, Carotid and humeral Doppler ultrasound, Trans-thoracic echocardiography 2D and 3D) * Pulmonary and auditory assesment ( Respiratory Functional Exploration, Tonal audiogram) * Blood tests
HEGP
Paris, Paris, France
Centre Paul Papin
Angers, France
CHU Besançon Jean MINJOZ
Besançon, France
Institut Bergonié
Bordeaux, France
CH Fleyriat
Bourg-en-Bresse, France
Centre François Baclesse
Caen, France
Centre Jean Perrin
Clermont-Ferrand, France
Centre Léon Berard
Lyon, France
Institut Paoli Calmettes
Marseille, France
Centre Catherine de Sienne
Nantes, France
...and 9 more locations
The chronic fatigue by questionnaires
Time frame: 2 years after surgery
The late sequelae of chemotherapy, particularly cardiovascular and pulmonary disorders, in adult patients in remission of a rare cancer of the ovary treated by surgery, supplemented or not by chemotherapy.
Time frame: 2 years after surgery
The quality of life by questionnaires
Time frame: 2 years after surgery
The fertility monitoring by questionnaires
Time frame: 2 years after surgery
The symptoms of menopause by questionnaires
Time frame: 2 years after surgery
Theimpact of cancer and its treatments on the trajectory and professional situation by questionnaires(access to work, professional ambition, financial situation ...);
Time frame: 2 years after surgery
The parental projects by age (≤ 45 years) by questionnaires
Time frame: 2 years after surgery
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