Fatigue due to cancer and its treatment (for example, radiation therapy) can interfere with quality of life and can linger long after treatment has ended, yet research examining preventative approaches has produced limited clinical benefit. The proposed study will provide information about systematic light exposure for the prevention of fatigue in prostate cancer patients undergoing radiation therapy and will investigate how it works. This study would facilitate the development of this potential preventative treatment, giving health care providers and cancer survivors a much-needed tool to help with cancer-related fatigue.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Enrollment
75
30 minutes of intervention systematic light exposure daily
30 minutes of comparison systematic light exposure daily
Northwestern Univeristy Feinberg School of Medicine
Chicago, Illinois, United States
Fatigue FACIT-Fatigue scores
FACIT-Fatigue scores
Time frame: Baseline
Fatigue
FACIT-Fatigue scores
Time frame: Change from Baseline to the 4th week of the intervention
Fatigue
FACIT-Fatigue scores
Time frame: Change from Baseline to the 8th week of the intervention
Fatigue
FACIT-Fatigue scores
Time frame: Change from Baseline to 2 months after the intervention
Circadian activity rhythms
Actigraphy
Time frame: Baseline
Circadian activity rhythms
Actigraphy
Time frame: During the 4th week of the intervention
Circadian activity rhythms
Actigraphy
Time frame: During the 8th week of the intervention
Circadian activity rhythms
Actigraphy
Time frame: 2 months after the intervention
Sleep quality
Pittsburgh Sleep Quality Index (PSQI)
Time frame: Baseline
Sleep quality
Pittsburgh Sleep Quality Index (PSQI)
Time frame: During the 4th week of the intervention
Sleep quality
Pittsburgh Sleep Quality Index (PSQI)
Time frame: During the 8th week of the intervention
Sleep quality
Pittsburgh Sleep Quality Index (PSQI)
Time frame: 2 months after the intervention
Depressed mood
Center for Epidemiologic Studies Depression Scale (CESD). Score range is 0 to 60, where higher scores represent more symptomatology present.
Time frame: Baseline
Depressed mood
Center for Epidemiologic Studies Depression Scale (CESD). Score range is 0 to 60, where higher scores represent more symptomatology present.
Time frame: During the 4th week of the intervention
Depressed mood
Center for Epidemiologic Studies Depression Scale (CESD). Score range is 0 to 60, where higher scores represent more symptomatology present.
Time frame: During the 8th week of the intervention
Depressed mood
Center for Epidemiologic Studies Depression Scale (CESD). Score range is 0 to 60, where higher scores represent more symptomatology present.
Time frame: 2 months after the intervention
Cognitive Functioning
Psychometric Analysis of the Patient Assessment of Own Functioning Inventory (PAOFI)
Time frame: Baseline
Cognitive Functioning
Psychometric Analysis of the Patient Assessment of Own Functioning Inventory (PAOFI)
Time frame: During the 4th week of the intervention
Cognitive Functioning
Psychometric Analysis of the Patient Assessment of Own Functioning Inventory (PAOFI)
Time frame: During the 8th week of the intervention
Cognitive Functioning
Psychometric Analysis of the Patient Assessment of Own Functioning Inventory (PAOFI)
Time frame: 2 months after the intervention
Sexual and urinary functioning
3 items from the Sexual Adjustment Questionnaire \& 3 items from American Urological Association (AUA) symptom index
Time frame: Baseline
Sexual and urinary functioning
3 items from the Sexual Adjustment Questionnaire \& 3 items from American Urological Association (AUA) symptom index
Time frame: During the 4th week of the intervention
Sexual and urinary functioning
3 items from the Sexual Adjustment Questionnaire \& 3 items from American Urological Association (AUA) symptom index
Time frame: During the 8th week of the intervention
Sexual and urinary functioning
3 items from the Sexual Adjustment Questionnaire \& 3 items from American Urological Association (AUA) symptom index
Time frame: 2 months after the intervention
Cognitive functioning
Neuropsychological tests
Time frame: Baseline
Cognitive functioning
Neuropsychological tests
Time frame: During the 8th week of the intervention
Cognitive functioning
Neuropsychological tests
Time frame: 2 months after the intervention
Health-related quality of life
Functional Assessment of Cancer Therapy - Prostate (FACT-P). From Radiation Therapy Oncology Group: "The FACT-P is a multidimensional, self-report QoL instrument specifically designed for use with prostate cancer patients. It consists of 27 core items which assess patient function in four domains: Physical, Social/Family, Emotional, and Functional well-being."with prostate cancer patients. It consists of 27 core items which assess patient function in four domains: Physical, Social/Family, Emotional, and Functional well-being.
Time frame: Baseline
Health-related quality of life
Functional Assessment of Cancer Therapy - Prostate (FACT-P). From Radiation Therapy Oncology Group: "The FACT-P is a multidimensional, self-report QoL instrument specifically designed for use with prostate cancer patients. It consists of 27 core items which assess patient function in four domains: Physical, Social/Family, Emotional, and Functional well-being."
Time frame: During the 4th week of the intervention
Health-related quality of life
Functional Assessment of Cancer Therapy - Prostate (FACT-P). From Radiation Therapy Oncology Group: "The FACT-P is a multidimensional, self-report QoL instrument specifically designed for use with prostate cancer patients. It consists of 27 core items which assess patient function in four domains: Physical, Social/Family, Emotional, and Functional well-being."with prostate cancer patients (1, 2, 3). It consists of 27 core items which assess patient function in four domains: Physical, Social/Family, Emotional, and Functional well-being.
Time frame: During the 8th week of the intervention
Health-related quality of life
Functional Assessment of Cancer Therapy - Prostate (FACT-P). From Radiation Therapy Oncology Group: "The FACT-P is a multidimensional, self-report QoL instrument specifically designed for use with prostate cancer patients. It consists of 27 core items which assess patient function in four domains: Physical, Social/Family, Emotional, and Functional well-being."with prostate cancer patients (1, 2, 3). It consists of 27 core items which assess patient function in four domains: Physical, Social/Family, Emotional, and Functional well-being.
Time frame: 2 months after the intervention
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