This is a sample study that will collect biological samples (blood, tumor tissue, ascites, and/or other fluids) from gynecological cancer patients for biomarker research. In addition, the results of the testing done on the samples will be given to the participant's treating physician who may use the information to guide treatment decisions.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
510
Tumour tissue will be taken from samples already removed from surgery or biopsy or by new tumour biopsies: * At the time of diagnosis or progression * Any surgical procedures for management of tumour related medical conditions * At each subsequent relapse or disease progression
Blood samples will be taken: * At the time of first diagnosis * About 1 week after starting any treatment * At each radiological response assessment * At each subsequent relapse or disease progression
Ascites will be collected if paracentesis is required during any of the following time points: * At the time of diagnosis or progression * Any surgical procedures for management of tumour related medical conditions * At each subsequent relapse or disease progression
Royal Victoria Regional Health Centre
Barrie, Ontario, Canada
RECRUITINGJuravinski Cancer Centre
Hamilton, Ontario, Canada
ACTIVE_NOT_RECRUITINGKingston Health Sciences Centre
Kingston, Ontario, Canada
Genomic and immune signatures in terms of progression free survival
Short term (1-2 years) versus long term (5-10 years) survival
Time frame: 10 years
Genomic and immune signatures in terms of overall survival
Short term (1-2 years) versus long term (5-10 years) survival
Time frame: 10 years
Genomic and immune signatures in terms of response to treatments
Time frame: 10 years
Genomic and immune signatures in terms of resistance to treatments
Time frame: 10 years
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Additional fluid will be collected at any time a procedure for clinical management that involves the drainage of fluid (i.e. thoracentesis, or drainage of cystic lesion) is required.
London Health Sciences Centre
London, Ontario, Canada
RECRUITINGThe Ottawa Hospital Cancer Centre
Ottawa, Ontario, Canada
RECRUITINGSunnybrook Health Sciences Centre
Toronto, Ontario, Canada
RECRUITINGPrincess Margaret Cancer Centre
Toronto, Ontario, Canada
RECRUITING