The primary purpose of this study is to compare pain after uterine artery embolization using non-spherical polyvinyl alcohol particles or tris-acryl gelatin microsphere in patients with symptomatic fibroids
Uterine artery embolization(UAE) is a minimally invasive treatment alternative to hysterectomy and myomectomy in symptomatic fibroids. However, post-procedural pain after UAE remains a major problem. The non-spherical polyvinyl alcohol particle and tri-acryl gelatin microsphere are two embolic materials used for UAE.Therefore, the aim of study is to compare pain intensity and inflammation after uterine artery embolization using non-spherical polyvinyl alcohol particles or tris-acryl gelatin microsphere in patients with symptomatic fibroids
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Enrollment
54
One of non-spherical polyvinyl alcohol particle or tris-acryl gelatin microsphere is used for embolic materials. All other processes are same.
Sesverance Hospital, Yonsei University College of Medicine
Seoul, South Korea
Pain intensity by numerical rating scale
0-10 numerical rating scale (0, no pain at all; 10, worst pain imaginable
Time frame: 0-24 h after UAE
C-reactive protein
mg/L
Time frame: 24 h after UAE
White blood cell count
/uL
Time frame: 24 h after UAE
Neutrophil percentage
Time frame: 24 h after UAE
Neutrophil-to-lymphocyte ratio
Time frame: 24 h after UAE
Platelet-to-lymphocyte ratio
Time frame: 24 h after UAE
Mean platelet volume
fL(femtolitre)
Time frame: 24 h after UAE
Sucessful rate at 3 month after UAE measured by MRI
Complete necrosis incidence
Time frame: 3 month after UAE
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