Study of Value of Dexamethasone Used in Ovulation Induction

Reproductive & Genetic Hospital of CITIC-Xiangya

Overview

This study intends to solve the following problems: whether use dexamethasone can obviously decrease transplant cancelling probability in fresh embryo transplant cycle or not, reduce time and frequency going to hospital repeatedly for patients need frozen embryo transplant or not, and reduce the economic burden for patients or not; By comparing pregnancy rate of single transplant, hope to make clear in IVF-ET treatment for patients progesterone increases to a certain level whether it is a good choice to transfer fresh embryo after dexamethasone treatment, or frozen embryo transplant is better.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Conditions

Infertility, Female

Interventions

Dexamethasone Oral TabletDRUG

Dexamethasone Oral Tablet，0.75mg/tablet

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 35 Years

Medical Language ↔ Plain English

Inclusion Criteria: \- female, 18 years old≤age≤35 years old, 18≤BMI≤25, standard patient, menstrual regularity Exclusion Criteria: Hyperprolactinemia, Thyroid dysfunction, uterine malformation ( inadequacy mediastinal uterus ≥1.0cm, Unicornate uterus, double uterus, T Angle of uterus, etc.), uterus adhesion, untreated hydrosalpinx , hysteromyoma（ hysteromyoma≥1.0 cm, and/or endometrial hysteromyoma≤1 cm), endometriosis, diabetes, hypertension, adrenal cortex hyperplasia, Cushing's syndrome, a pituitary amenorrhea

Locations (1)

Reproductive & Genetic Hospital of CITIC-XIANGYA

Changsha, Hunan, China

Outcomes

Primary Outcomes

cumulative pregnancy rate per oocyte retrieval cycle

Time frame: Until 28 day after embryo transferred

Data from ClinicalTrials.gov

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