Bioequivalence Study of 120 mg Etoricoxib Film-coated Tablets

Inclusion Criteria: 1. Healthy male and female subjects Healthy was defined as the absence of significant disease or clinically significant abnormal laboratory values on laboratory evaluation, medical history or physical examination during screening. 2. Aged 18 - 55 years inclusive. 3. Preferably non-smokers or smoke less than 10 cigarettes per day. 4. Able to participate and would provide written informed consent to participate. 5. BMI within 18 to 25 kg/m2. 6. Vital signs (after 10 minutes rest) were within the following ranges: SBP 100 - 120 mmHg ; DBP 60 - 80 mmHg; HR 60 - 90 bpm. Exclusion Criteria: 1. Personal/family history of allergy or hypersensitivity or contraindication to etoricoxib or allied drugs. 2. Pregnant or lactating women. 3. Any major illness in the past 90 days or clinically significant ongoing chronic illness 4. Presence of any clinically significant abnormal laboratory values during screening. 5. Positive Hepatitis B surface antigen (HBsAg), anti-HCV, or anti-HIV. 6. Clinically significant hematology abnormalities. 7. Clinically significant electrocardiogram (ECG) abnormalities. 8. Any surgical or medical condition (present or history) which might significantly alter the absorption, distribution, metabolism or excretion of the study drug, e.g. gastrointestinal disease including gastric or duodenal ulcers or history of gastric surgery. 9. Past history of anaphylaxis or angioedema. 10. History of drug or alcohol abuse within 12 months prior to screening for this study. 11. Participation in any clinical trial within the past 90 days calculated from the last visit. 12. History of any bleeding or coagulative disorders. 13. History of difficulty with donating blood or difficulty in accessibility of veins in left or right arm. 14. A donation or loss of 300 mL (or more) of blood within 3 months before this study's first dosing day. 15. Intake of any prescription, non-prescription drug, food supplement or herbal medicine within 14 days of this study's first dosing day.