Surgical Stress and Intracorporeal Anastomosis

Federico II University20 enrolled

Overview

The short-term advantages of minimally invasive colon resection have been well established in several randomized trials. A major factor in the development of morbidity is the surgical stress response with subsequent increased demand on the patient's reserves and immune competence. Although the advantage in term of stress response of laparoscopic surgery over open surgery has been widely reported, little is known about the role of Intracorporeal anastomosis. In an attempt to evaluate the surgical stress response after totally laparoscopic right colectomy a comparative study has been designed. Two surgical procedures will be evaluated: * Totally laparoscopic right colectomy with intracorporeal anastomosis (Experimental group) * Laparoscopic assisted right colectomy with extracorporeal anastomosis (Control group).

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Laparoscopic Right Colectomy

Interventions

Laparoscopic right colectomy for colorectal cancer with a standard vascular dissection, performing the anastomosis with a side-to-side mechanical anastomosis fashioned intracorporeally versus extra corporeally

Eligibility

Sex: ALLMin age: 18 YearsMax age: 100 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: All elective laparoscopic right colectomy for cancer Exclusion Criteria: Urgent procedures Immune depressant therapy Immune depressant disease Post-operative Complications

Locations (1)

University of Naples Federico II

Naples, Italy